KSV58445.1 protein (Acetivibrio ethanolgignens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KSV58445.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)

Predicted Functional Partners:

accD

0.830

KSV60040.1

0.810

KSV59735.1

0.764

KSV58080.1

0.763

KSV59763.1

0.761

KSV59728.1

0.729

KSV59731.1

0.729

KSV58119.1

0.721

KSV58360.1

0.716

KSV59320.1

0.690

Your Current Organism:

Acetivibrio ethanolgignens

NCBI taxonomy Id: 290052
Other names: A. ethanolgignens, ATCC 33324, Acetivibrio ethanoligignens, DSM 3005, LMG 7055, LMG:7055, strain 77-6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KSV58080.1	KSV58119.1	ASU35_03330	ASU35_03550	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.678
KSV58080.1	KSV58360.1	ASU35_03330	ASU35_02870	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.627
KSV58080.1	KSV58445.1	ASU35_03330	ASU35_12885	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.763
KSV58080.1	KSV59320.1	ASU35_03330	ASU35_09605	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.733
KSV58080.1	KSV59728.1	ASU35_03330	ASU35_08225	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.683
KSV58080.1	KSV59731.1	ASU35_03330	ASU35_08240	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.591
KSV58080.1	KSV59735.1	ASU35_03330	ASU35_08260	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.770
KSV58119.1	KSV58080.1	ASU35_03550	ASU35_03330	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.678
KSV58119.1	KSV58360.1	ASU35_03550	ASU35_02870	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.729
KSV58119.1	KSV58445.1	ASU35_03550	ASU35_12885	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.721
KSV58119.1	KSV59320.1	ASU35_03550	ASU35_09605	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.688
KSV58119.1	KSV59728.1	ASU35_03550	ASU35_08225	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.767
KSV58119.1	KSV59731.1	ASU35_03550	ASU35_08240	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.759
KSV58119.1	KSV59735.1	ASU35_03550	ASU35_08260	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.757
KSV58360.1	KSV58080.1	ASU35_02870	ASU35_03330	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.627
KSV58360.1	KSV58119.1	ASU35_02870	ASU35_03550	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.729
KSV58360.1	KSV58445.1	ASU35_02870	ASU35_12885	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.716
KSV58360.1	KSV59320.1	ASU35_02870	ASU35_09605	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.523
KSV58360.1	KSV59728.1	ASU35_02870	ASU35_08225	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.635
KSV58360.1	KSV59731.1	ASU35_02870	ASU35_08240	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.709

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Network Stats

number of nodes:

11

number of edges:

18

average node degree:

3.27

avg. local clustering coefficient:

0.898

expected number of edges:

13

PPI enrichment p-value:

0.0888

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006352

DNA-templated transcription, initiation

9 of 46

1.92

4.77

1.31e-13

GO:0050896

Response to stimulus

9 of 308

1.1

1.4

4.91e-08

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016987

Sigma factor activity

9 of 46

1.92

4.83

7.61e-14

GO:0140110

Transcription regulator activity

11 of 162

1.46

2.95

7.61e-14

GO:0003677

DNA binding

9 of 372

1.01

1.15

1.11e-06

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

9 of 1163

0.52

0.36

0.0138

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5963

FecR protein, and RNA polymerase sigma-70, Bacteroidetes type

11 of 42

2.05

6.79

1.23e-19

CL:5970

FecR protein, and RNA polymerase sigma-70, Bacteroidetes type

9 of 25

2.19

6.62

1.32e-16

CL:5973

FecR protein, and RNA polymerase sigma-70, Bacteroidetes type

7 of 17

2.24

5.45

1.12e-12

CL:5974

FecR protein, and RNA polymerase sigma-70 region 4

5 of 11

2.29

3.94

9.48e-09

CL:5986

RNA polymerase sigma-70 region 4, and FecR protein

3 of 5

2.41

2.3

4.42e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02020

Two-component system

11 of 459

1.01

1.29

1.05e-09

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000428

DNA-directed RNA polymerase complex

9 of 76

1.7

3.71

2.14e-12

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0731

Sigma factor

9 of 43

1.95

5.13

1.33e-14

KW-0238

DNA-binding

9 of 192

1.3

2.03

1.05e-09

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF04542

Sigma-70 region 2

9 of 42

1.96

5.07

3.49e-14

PF08281

Sigma-70, region 4

4 of 24

1.85

1.87

0.00011

PF04545

Sigma-70, region 4

3 of 16

1.9

1.36

0.0020

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR007627

RNA polymerase sigma-70 region 2

9 of 40

1.98

5.09

5.76e-14

IPR039425

RNA polymerase sigma-70 like

9 of 41

1.97

5.05

5.76e-14

IPR014327

RNA polymerase sigma-70, Bacteroidetes type

7 of 20

2.17

4.99

7.64e-12

IPR013325

RNA polymerase sigma factor, region 2

9 of 43

1.95

4.97

5.76e-14

IPR014284

RNA polymerase sigma-70 like domain

9 of 44

1.94

4.94

5.76e-14

(more ...)

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