STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PENO1_109450Guanosine diphosphatase; Belongs to the GDA1/CD39 NTPase family. (547 aa)    
Predicted Functional Partners:
PENO1_005580
Nucleoside phosphatase GDA1/CD39; Belongs to the GDA1/CD39 NTPase family.
  
 
0.852
PENO1_021330
NAD/GMP synthase.
   
 
 0.722
PENO1_022730
Alkaline phosphatase-like, alpha/beta/alpha.
    
 0.710
PENO1_079020
Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote.
    
  0.703
PENO1_010600
Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
   
 
 0.697
ADK2
GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
   
 
 0.694
PENO1_098430
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
   
 
  0.679
PENO1_073690
Nucleotide-binding, alpha-beta plait.
     
 0.670
PENO1_066920
AMP deaminase.
     
 0.670
PENO1_053490
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
     
 0.670
Your Current Organism:
Penicillium sp. occitanis
NCBI taxonomy Id: 290292
Other names: P. sp. 'occitanis', Penicillium occitanis, Penicillium sp. 'occitanis'
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