STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMGR23-hydroxy-3-methylglutaryl coenzyme A reductase. (433 aa)    
Predicted Functional Partners:
HMGS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.986
R1D3V8_EMIHU
HMG_CoA_synt_N domain-containing protein.
  
 
 0.986
HMGS2
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.986
MVK1
Mevalonate kinase.
  
 0.969
R1EVA3_EMIHU
Mevalonate kinase.
  
 0.969
MVK2
Mevalonate kinase.
  
 0.969
HMGR1
3-hydroxy-3-methyl-glutaryl-CoA reductase.
  
  
0.904
HMGR3
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
  
 
0.900
R1D868_EMIHU
Uncharacterized protein.
   
 
 0.816
MVD1
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
  
  
 0.788
Your Current Organism:
Emiliania huxleyi
NCBI taxonomy Id: 2903
Other names: E. huxleyi, Emiliania huxleyi (Lohmann) W.W.Hay & H.P.Mohler, Gephyrocapsa huxleyi, Pontosphaera huxleyi
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