STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
R1BRG3_EMIHUD-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (108 aa)    
Predicted Functional Partners:
R1C2B5_EMIHU
Tryptophane synthase.
  
 
 0.659
R1CPT2_EMIHU
Inositol-1-monophosphatase.
  
  
 0.629
R1CUZ1_EMIHU
Inositol-1-monophosphatase.
  
  
 0.629
R1DZJ5_EMIHU
Inositol-1-monophosphatase.
  
  
 0.629
R1CMK3_EMIHU
AB hydrolase-1 domain-containing protein.
  
 
 0.583
R1DGV6_EMIHU
Uncharacterized protein.
  
 
 0.583
R1ENI5_EMIHU
Uncharacterized protein.
  
 
 0.583
R1EQ71_EMIHU
Uncharacterized protein.
  
 
 0.583
R1DPQ4_EMIHU
TPR domain-containing protein.
     
 0.580
R1E700_EMIHU
Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
     
 0.571
Your Current Organism:
Emiliania huxleyi
NCBI taxonomy Id: 2903
Other names: E. huxleyi, Emiliania huxleyi (Lohmann) W.W.Hay & H.P.Mohler, Gephyrocapsa huxleyi, Pontosphaera huxleyi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.