R1DKW9_EMIHU protein (Emiliania huxleyi) - STRING interaction network

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R1DKW9_EMIHU

Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (513 aa)

Predicted Functional Partners:

R1DP44_EMIHU

0.960

R1FQ80_EMIHU

0.955

R1DWC9_EMIHU

0.932

HMGS1

0.925

R1D3V8_EMIHU

0.925

HMGS2

0.925

ACAT1

0.887

R1D0K6_EMIHU

0.887

R1EFT0_EMIHU

0.559

R1ENS0_EMIHU

0.499

Your Current Organism:

Emiliania huxleyi

NCBI taxonomy Id: 2903
Other names: E. huxleyi, Emiliania huxleyi (Lohmann) W.W.Hay & H.P.Mohler, Gephyrocapsa huxleyi, Pontosphaera huxleyi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAT1	HMGS1	R1C8R5	R1CY43	Acetyl-CoA acetyl transferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.988
ACAT1	HMGS2	R1C8R5	R1DE09	Acetyl-CoA acetyl transferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.988
ACAT1	R1D0K6_EMIHU	R1C8R5	R1D0K6	Acetyl-CoA acetyl transferase; Belongs to the thiolase-like superfamily. Thiolase family.	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.900
ACAT1	R1D3V8_EMIHU	R1C8R5	R1D3V8	Acetyl-CoA acetyl transferase; Belongs to the thiolase-like superfamily. Thiolase family.	HMG_CoA_synt_N domain-containing protein.	0.990
ACAT1	R1DKW9_EMIHU	R1C8R5	R1DKW9	Acetyl-CoA acetyl transferase; Belongs to the thiolase-like superfamily. Thiolase family.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.887
ACAT1	R1DP44_EMIHU	R1C8R5	R1DP44	Acetyl-CoA acetyl transferase; Belongs to the thiolase-like superfamily. Thiolase family.	Hydroxymethylglutaryl-CoA lyase.	0.954
ACAT1	R1DWC9_EMIHU	R1C8R5	R1DWC9	Acetyl-CoA acetyl transferase; Belongs to the thiolase-like superfamily. Thiolase family.	3HCDH_N domain-containing protein.	0.872
ACAT1	R1EFT0_EMIHU	R1C8R5	R1EFT0	Acetyl-CoA acetyl transferase; Belongs to the thiolase-like superfamily. Thiolase family.	ASL_C domain-containing protein.	0.496
ACAT1	R1FQ80_EMIHU	R1C8R5	R1FQ80	Acetyl-CoA acetyl transferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.931
HMGS1	ACAT1	R1CY43	R1C8R5	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acetyl transferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.988
HMGS1	HMGS2	R1CY43	R1DE09	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.901
HMGS1	R1D0K6_EMIHU	R1CY43	R1D0K6	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.988
HMGS1	R1D3V8_EMIHU	R1CY43	R1D3V8	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	HMG_CoA_synt_N domain-containing protein.	0.914
HMGS1	R1DKW9_EMIHU	R1CY43	R1DKW9	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.925
HMGS1	R1DP44_EMIHU	R1CY43	R1DP44	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Hydroxymethylglutaryl-CoA lyase.	0.944
HMGS1	R1DWC9_EMIHU	R1CY43	R1DWC9	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3HCDH_N domain-containing protein.	0.904
HMGS1	R1ENS0_EMIHU	R1CY43	R1ENS0	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.909
HMGS1	R1FQ80_EMIHU	R1CY43	R1FQ80	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.991
HMGS2	ACAT1	R1DE09	R1C8R5	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acetyl transferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.988
HMGS2	HMGS1	R1DE09	R1CY43	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.901

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