node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
R1B493_EMIHU | R1BFN3_EMIHU | R1B493 | R1BFN3 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Glutamine amidotransferase. | 0.979 |
R1B493_EMIHU | R1CJY6_EMIHU | R1B493 | R1CJY6 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylosuccinate synthase. | 0.979 |
R1B493_EMIHU | R1DGA9_EMIHU | R1B493 | R1DGA9 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | A_deaminase domain-containing protein. | 0.976 |
R1B493_EMIHU | R1EL43_EMIHU | R1B493 | R1EL43 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.974 |
R1B493_EMIHU | R1FFU5_EMIHU | R1B493 | R1FFU5 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.955 |
R1B493_EMIHU | R1FN82_EMIHU | R1B493 | R1FN82 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.931 |
R1B493_EMIHU | R1FQK5_EMIHU | R1B493 | R1FQK5 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Glutamine amidotransferase. | 0.979 |
R1B493_EMIHU | R1G1K8_EMIHU | R1B493 | R1G1K8 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.955 |
R1BFN3_EMIHU | R1B493_EMIHU | R1BFN3 | R1B493 | Glutamine amidotransferase. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.979 |
R1BFN3_EMIHU | R1CJY6_EMIHU | R1BFN3 | R1CJY6 | Glutamine amidotransferase. | Adenylosuccinate synthase. | 0.770 |
R1BFN3_EMIHU | R1DGA9_EMIHU | R1BFN3 | R1DGA9 | Glutamine amidotransferase. | A_deaminase domain-containing protein. | 0.550 |
R1BFN3_EMIHU | R1EL43_EMIHU | R1BFN3 | R1EL43 | Glutamine amidotransferase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.770 |
R1BFN3_EMIHU | R1FFU5_EMIHU | R1BFN3 | R1FFU5 | Glutamine amidotransferase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.994 |
R1BFN3_EMIHU | R1FN82_EMIHU | R1BFN3 | R1FN82 | Glutamine amidotransferase. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.952 |
R1BFN3_EMIHU | R1FQK5_EMIHU | R1BFN3 | R1FQK5 | Glutamine amidotransferase. | Glutamine amidotransferase. | 0.900 |
R1BFN3_EMIHU | R1G1K8_EMIHU | R1BFN3 | R1G1K8 | Glutamine amidotransferase. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.993 |
R1CJY6_EMIHU | R1B493_EMIHU | R1CJY6 | R1B493 | Adenylosuccinate synthase. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.979 |
R1CJY6_EMIHU | R1BFN3_EMIHU | R1CJY6 | R1BFN3 | Adenylosuccinate synthase. | Glutamine amidotransferase. | 0.770 |
R1CJY6_EMIHU | R1DGA9_EMIHU | R1CJY6 | R1DGA9 | Adenylosuccinate synthase. | A_deaminase domain-containing protein. | 0.952 |
R1CJY6_EMIHU | R1EL43_EMIHU | R1CJY6 | R1EL43 | Adenylosuccinate synthase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.900 |