node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Clim_0185 | Clim_1404 | Clim_0185 | Clim_1404 | TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; KEGG: cph:Cpha266_0222 elongation factor G. | PFAM: Endoribonuclease L-PSP; KEGG: cph:Cpha266_1530 endoribonuclease L-PSP. | 0.671 |
Clim_0185 | metG | Clim_0185 | Clim_1190 | TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; KEGG: cph:Cpha266_0222 elongation factor G. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.420 |
Clim_0829 | Clim_1404 | Clim_0829 | Clim_1404 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | PFAM: Endoribonuclease L-PSP; KEGG: cph:Cpha266_1530 endoribonuclease L-PSP. | 0.433 |
Clim_0829 | Clim_1407 | Clim_0829 | Clim_1407 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cph:Cpha266_1533 phosphomethylpyrimidine kinase. | 0.493 |
Clim_1404 | Clim_0185 | Clim_1404 | Clim_0185 | PFAM: Endoribonuclease L-PSP; KEGG: cph:Cpha266_1530 endoribonuclease L-PSP. | TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; KEGG: cph:Cpha266_0222 elongation factor G. | 0.671 |
Clim_1404 | Clim_0829 | Clim_1404 | Clim_0829 | PFAM: Endoribonuclease L-PSP; KEGG: cph:Cpha266_1530 endoribonuclease L-PSP. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.433 |
Clim_1404 | Clim_1405 | Clim_1404 | Clim_1405 | PFAM: Endoribonuclease L-PSP; KEGG: cph:Cpha266_1530 endoribonuclease L-PSP. | PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase. | 0.509 |
Clim_1404 | Clim_1407 | Clim_1404 | Clim_1407 | PFAM: Endoribonuclease L-PSP; KEGG: cph:Cpha266_1530 endoribonuclease L-PSP. | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cph:Cpha266_1533 phosphomethylpyrimidine kinase. | 0.509 |
Clim_1404 | fusA | Clim_1404 | Clim_2232 | PFAM: Endoribonuclease L-PSP; KEGG: cph:Cpha266_1530 endoribonuclease L-PSP. | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | 0.671 |
Clim_1404 | metG | Clim_1404 | Clim_1190 | PFAM: Endoribonuclease L-PSP; KEGG: cph:Cpha266_1530 endoribonuclease L-PSP. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.435 |
Clim_1404 | msrA | Clim_1404 | Clim_1371 | PFAM: Endoribonuclease L-PSP; KEGG: cph:Cpha266_1530 endoribonuclease L-PSP. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.462 |
Clim_1404 | nnrD | Clim_1404 | Clim_1204 | PFAM: Endoribonuclease L-PSP; KEGG: cph:Cpha266_1530 endoribonuclease L-PSP. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.446 |
Clim_1404 | thiE | Clim_1404 | Clim_1406 | PFAM: Endoribonuclease L-PSP; KEGG: cph:Cpha266_1530 endoribonuclease L-PSP. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.509 |
Clim_1405 | Clim_1404 | Clim_1405 | Clim_1404 | PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase. | PFAM: Endoribonuclease L-PSP; KEGG: cph:Cpha266_1530 endoribonuclease L-PSP. | 0.509 |
Clim_1405 | Clim_1407 | Clim_1405 | Clim_1407 | PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase. | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cph:Cpha266_1533 phosphomethylpyrimidine kinase. | 0.998 |
Clim_1405 | thiE | Clim_1405 | Clim_1406 | PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.981 |
Clim_1407 | Clim_0829 | Clim_1407 | Clim_0829 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cph:Cpha266_1533 phosphomethylpyrimidine kinase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.493 |
Clim_1407 | Clim_1404 | Clim_1407 | Clim_1404 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cph:Cpha266_1533 phosphomethylpyrimidine kinase. | PFAM: Endoribonuclease L-PSP; KEGG: cph:Cpha266_1530 endoribonuclease L-PSP. | 0.509 |
Clim_1407 | Clim_1405 | Clim_1407 | Clim_1405 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cph:Cpha266_1533 phosphomethylpyrimidine kinase. | PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase. | 0.998 |
Clim_1407 | thiE | Clim_1407 | Clim_1406 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cph:Cpha266_1533 phosphomethylpyrimidine kinase. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |