node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Clim_0664 | Clim_0666 | Clim_0664 | Clim_0666 | PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: cph:Cpha266_0729 thiamine biosynthesis protein ThiH. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: cph:Cpha266_0731 thiamine biosynthesis protein ThiS. | 0.928 |
Clim_0664 | Clim_1405 | Clim_0664 | Clim_1405 | PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: cph:Cpha266_0729 thiamine biosynthesis protein ThiH. | PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase. | 0.746 |
Clim_0664 | Clim_1407 | Clim_0664 | Clim_1407 | PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: cph:Cpha266_0729 thiamine biosynthesis protein ThiH. | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cph:Cpha266_1533 phosphomethylpyrimidine kinase. | 0.480 |
Clim_0664 | thiC | Clim_0664 | Clim_1669 | PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: cph:Cpha266_0729 thiamine biosynthesis protein ThiH. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.911 |
Clim_0664 | thiE | Clim_0664 | Clim_1406 | PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: cph:Cpha266_0729 thiamine biosynthesis protein ThiH. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.746 |
Clim_0664 | thiG | Clim_0664 | Clim_0665 | PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: cph:Cpha266_0729 thiamine biosynthesis protein ThiH. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.999 |
Clim_0666 | Clim_0664 | Clim_0666 | Clim_0664 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: cph:Cpha266_0731 thiamine biosynthesis protein ThiS. | PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: cph:Cpha266_0729 thiamine biosynthesis protein ThiH. | 0.928 |
Clim_0666 | Clim_1405 | Clim_0666 | Clim_1405 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: cph:Cpha266_0731 thiamine biosynthesis protein ThiS. | PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase. | 0.730 |
Clim_0666 | Clim_1407 | Clim_0666 | Clim_1407 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: cph:Cpha266_0731 thiamine biosynthesis protein ThiS. | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cph:Cpha266_1533 phosphomethylpyrimidine kinase. | 0.798 |
Clim_0666 | thiC | Clim_0666 | Clim_1669 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: cph:Cpha266_0731 thiamine biosynthesis protein ThiS. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.851 |
Clim_0666 | thiE | Clim_0666 | Clim_1406 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: cph:Cpha266_0731 thiamine biosynthesis protein ThiS. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.730 |
Clim_0666 | thiG | Clim_0666 | Clim_0665 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: cph:Cpha266_0731 thiamine biosynthesis protein ThiS. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.994 |
Clim_1405 | Clim_0664 | Clim_1405 | Clim_0664 | PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase. | PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: cph:Cpha266_0729 thiamine biosynthesis protein ThiH. | 0.746 |
Clim_1405 | Clim_0666 | Clim_1405 | Clim_0666 | PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: cph:Cpha266_0731 thiamine biosynthesis protein ThiS. | 0.730 |
Clim_1405 | Clim_1407 | Clim_1405 | Clim_1407 | PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase. | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cph:Cpha266_1533 phosphomethylpyrimidine kinase. | 0.998 |
Clim_1405 | Clim_2447 | Clim_1405 | Clim_2447 | PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase. | PFAM: Alkaline phosphatase; KEGG: cph:Cpha266_2693 alkaline phosphatase; Belongs to the alkaline phosphatase family. | 0.900 |
Clim_1405 | rsgA | Clim_1405 | Clim_0387 | PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase. | Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | 0.902 |
Clim_1405 | rsgA-2 | Clim_1405 | Clim_2240 | PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase. | GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | 0.902 |
Clim_1405 | thiC | Clim_1405 | Clim_1669 | PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.784 |
Clim_1405 | thiE | Clim_1405 | Clim_1406 | PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.981 |