Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Clim_1985Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (301 aa)    
Predicted Functional Partners:
Clim_2141
KEGG: plt:Plut_0268 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HppK; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK.
 
 0.999
Clim_0322
TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; KEGG: cph:Cpha266_0391 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family.
 
 0.996
Clim_2140
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.989
folE
PFAM: GTP cyclohydrolase I; KEGG: cph:Cpha266_0976 GTP cyclohydrolase I.
  
 0.980
Clim_1992
TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; KEGG: cph:Cpha266_0499 para-aminobenzoate synthase, subunit I.
 
 
 0.972
Clim_0249
PFAM: beta-lactamase domain protein; KEGG: cph:Cpha266_0308 beta-lactamase domain protein.
     
  0.900
Clim_1984
PFAM: peptidase M50; KEGG: cph:Cpha266_0506 peptidase M50.
  
    0.777
Clim_2067
KEGG: ppd:Ppro_0225 hypothetical protein.
  
  
 0.775
Clim_0394
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: cph:Cpha266_2037 glutamine amidotransferase of anthranilate synthase.
 
  
 0.611
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.583
Your Current Organism:
Chlorobium limicola
NCBI taxonomy Id: 290315
Other names: C. limicola DSM 245, Chlorobium limicola 6330, Chlorobium limicola DSM 245, Chlorobium limicola DSMZ 245(T), Chlorobium limicola str. DSM 245, Chlorobium limicola strain DSM 245
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