close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lipALipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (287 aa)    
Predicted Functional Partners:
ABL65680.1
PFAM: biotin/lipoate A/B protein ligase; KEGG: plt:Plut_1329 lipoate-protein ligase A-like.
  
 
 0.940
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.913
ABL65308.1
PFAM: Semialdehyde dehydrogenase, NAD - binding; NAD-dependent epimerase/dehydratase; Male sterility C-terminal domain; KEGG: cch:Cag_1016 hypothetical protein.
       0.727
ABL65309.1
KEGG: plt:Plut_1085 hypothetical protein.
       0.727
ABL65653.1
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: plt:Plut_0784 dihydrolipoamide dehydrogenase.
 
  
 0.638
ABL64780.1
PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: bxe:Bxe_A2810 dihydrolipoamide dehydrogenase.
 
  
 0.601
ABL65307.1
KEGG: cte:CT1463 hypothetical protein.
       0.458
obg
GTP1/OBG sub domain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
 
      0.430
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.405
Your Current Organism:
Chlorobium phaeobacteroides DSM 266
NCBI taxonomy Id: 290317
Other names: C. phaeobacteroides DSM 266, Chlorobium phaeobacteroides DSMZ 266(T), Chlorobium phaeobacteroides str. DSM 266, Chlorobium phaeobacteroides strain DSM 266
Server load: medium (58%) [HD]