STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cvib_1039KEGG: plt:Plut_1292 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. (689 aa)    
Predicted Functional Partners:
Cvib_1038
Heterodimeric methylmalonyl-CoA mutase small subunit; KEGG: plt:Plut_1291 methylmalonyl-CoA mutase.
 
0.999
Cvib_1040
TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: plt:Plut_1293 arginine/ornithine transport system ATPase.
  
 0.996
Cvib_1037
methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: plt:Plut_1289 lactoylglutathione lyase.
  
 0.994
Cvib_1597
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: plt:Plut_1954 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
    
 0.949
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.938
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.927
Cvib_1598
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: plt:Plut_1955 ferrodoxin oxidoreductase beta subunit.
     
 0.927
Cvib_1407
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: plt:Plut_1617 pyruvate:ferredoxin (flavodoxin) oxidoreductase.
    
 0.926
Cvib_0866
PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: plt:Plut_1062 citrate lyase, subunit 2.
    
 0.909
Cvib_1018
PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: plt:Plut_1267 oxaloacetate decarboxylase, alpha subunit.
    
 0.903
Your Current Organism:
Chlorobium phaeovibrioides
NCBI taxonomy Id: 290318
Other names: C. phaeovibrioides DSM 265, Chlorobium phaeovibrioides DSM 265, Chlorobium vibrioforme f. thiosulfatophilum DSM 265, Prosthecochloris vibrioformis DSM 265
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