STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_00209Hypothetical protein; KEGG: reh:H16_A2563 1.7e-58 rpoE1; DNA-directed RNA polymerase sigma subunit (RpoE,sigma24) K00960; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Psort location: Cytoplasmic, score:8.96; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa)    
Predicted Functional Partners:
CKO_00210
Hypothetical protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrad [...]
 
 
 0.994
CKO_00211
Hypothetical protein; COG: COG3026 Negative regulator of sigma E activity; Psort location: Periplasmic, score:9.76.
 
 
 0.895
rpoC
Hypothetical protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.781
CKO_00212
Hypothetical protein; COG: COG3086 Positive regulator of sigma E activity.
  
  
 0.769
rpoB
Hypothetical protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.762
rpoA
Hypothetical protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.721
rpoZ
Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.720
CKO_01068
Hypothetical protein; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
    
   0.669
CKO_00232
Hypothetical protein; COG: NOG06210 non supervised orthologous group.
    
 
 0.642
CKO_01002
Hypothetical protein; KEGG: sec:SC1977 2.5e-229 fliI; flagellum-specific ATP synthase K02412; COG: COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; Psort location: Cytoplasmic, score:8.96.
    
 
 0.632
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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