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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_00212Hypothetical protein; COG: COG3086 Positive regulator of sigma E activity. (159 aa)    
Predicted Functional Partners:
CKO_00211
Hypothetical protein; COG: COG3026 Negative regulator of sigma E activity; Psort location: Periplasmic, score:9.76.
 
  
 0.986
CKO_00210
Hypothetical protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrad [...]
 
  
 0.919
CKO_00209
Hypothetical protein; KEGG: reh:H16_A2563 1.7e-58 rpoE1; DNA-directed RNA polymerase sigma subunit (RpoE,sigma24) K00960; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Psort location: Cytoplasmic, score:8.96; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.769
CKO_04821
Hypothetical protein; COG: NOG06324 non supervised orthologous group; Psort location: CytoplasmicMembrane, score:9.50.
  
     0.721
CKO_04654
COG: COG3164 Predicted membrane protein; Psort location: OuterMembrane, score:9.52.
  
     0.691
rnfG
Hypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
 
   
 0.656
CKO_01030
Hypothetical protein; COG: NOG13894 non supervised orthologous group.
  
     0.638
CKO_00214
Hypothetical protein; KEGG: ecp:ECP_2570 5.0e-169 signal peptidase I K03100; COG: COG0681 Signal peptidase I; Psort location: CytoplasmicMembrane, score:10.00; Belongs to the peptidase S26 family.
 
     0.572
CKO_02304
COG: COG3637 Opacity protein and related surface antigens; Psort location: OuterMembrane, score:10.00.
  
     0.551
CKO_01124
Hypothetical protein; KEGG: spt:SPA0993 1.7e-33 holE; DNA polymerase III, theta subunit K02345; COG: NOG13893 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96.
  
     0.538
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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