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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purMHypothetical protein; KEGG: sbo:SBO_2520 8.2e-137 purM; phosphoribosylaminoimidazole synthetase K01933; COG: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; Psort location: Cytoplasmic, score:8.96. (271 aa)    
Predicted Functional Partners:
purL
Hypothetical protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
 
 
 0.999
purN
Hypothetical protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 0.999
purD
Hypothetical protein; KEGG: ecp:ECP_4218 5.2e-222 phosphoribosylamine-glycine ligase K01945; COG: COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family.
  
 0.997
purK
Hypothetical protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
 
 
 0.996
purF
Hypothetical protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.992
purE
Hypothetical protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
  
 0.979
purH
Hypothetical protein; KEGG: spt:SPA4013 4.4e-273 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase (bifunctional enzyme) K00602:K01492; COG: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).
 
  
 0.977
purC
Hypothetical protein; KEGG: ecj:JW2461 7.2e-122 purC; phosphoribosylaminoimidazole-succinocarboxamide synthetase K01923; COG: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase.
 
  
 0.975
CKO_01840
Hypothetical protein; KEGG: ssn:SSO_1149 2.9e-237 purB; adenylosuccinate lyase K01756; COG: COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
 0.905
carA
Hypothetical protein; KEGG: eci:UTI89_C0036 1.4e-198 carA; carbamoyl-phosphate synthase small chain K01956; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score:8.96; Belongs to the CarA family.
 
  
 0.902
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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