close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_00294Hypothetical protein; KEGG: bcz:BCZK0244 2.2e-07 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; COG: COG2233 Xanthine/uracil permeases; Psort location: CytoplasmicMembrane, score:10.00. (429 aa)    
Predicted Functional Partners:
pyrB
Hypothetical protein; KEGG: sec:SC4315 1.4e-157 pyrB; aspartate carbamoyltransferase, catalytic subunit K00609; COG: COG0540 Aspartate carbamoyltransferase, catalytic chain; Psort location: Cytoplasmic, score:9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.885
CKO_00943
Hypothetical protein; KEGG: aha:AHA_2602 3.5e-136 dihydroorotase K01465; COG: COG0044 Dihydroorotase and related cyclic amidohydrolases; Psort location: Cytoplasmic, score:8.96.
  
  
 0.883
pyrF
Hypothetical protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.878
pyrE
Hypothetical protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.875
pyrD
Hypothetical protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
  
 0.869
upp
Hypothetical protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
  
 0.862
carA
Hypothetical protein; KEGG: eci:UTI89_C0036 1.4e-198 carA; carbamoyl-phosphate synthase small chain K01956; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score:8.96; Belongs to the CarA family.
  
  
 0.858
CKO_01018
Hypothetical protein; KEGG: lic:LIC12268 0.0034 putative glycolate oxidase K00016; COG: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Psort location: Cytoplasmic, score:8.96.
  
  
 0.841
carB
Hypothetical protein; KEGG: stm:STM0067 0. carB; carbamoyl-phosphate synthase, large subunit K01955; COG: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family.
  
  
 0.841
pyrI
Hypothetical protein; Involved in allosteric regulation of aspartate carbamoyltransferase.
  
  
 0.821
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: low (34%) [HD]