STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfeWHypothetical protein; KEGG: oih:OB0667 4.4e-51 beta-lactamase K01467; COG: COG1680 Beta-lactamase class C and other penicillin binding proteins; Psort location: Periplasmic, score:9.76; Belongs to the peptidase S12 family. YfeW subfamily. (434 aa)    
Predicted Functional Partners:
nagZ
Hypothetical protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
  
 0.934
CKO_04583
Hypothetical protein; KEGG: ssn:SSO_3330 9.8e-244 dacB; D-alanyl-D-alanine carboxypeptidase fraction B K07259; COG: COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4).
     
 0.913
CKO_00774
Hypothetical protein; KEGG: stm:STM2062 5.8e-191 dacD; DD-carboxypeptidase, penicillin-binding protein 6b K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Psort location: CytoplasmicMembrane, score:8.60; Belongs to the peptidase S11 family.
     
 0.907
CKO_02270
Hypothetical protein; KEGG: ecc:c0924 1.3e-207 dacC; penicillin-binding protein 6 precursor K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
     
 0.907
CKO_02526
Hypothetical protein; KEGG: sec:SC0666 1.8e-212 dacA; D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5 K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
     
 0.907
murQ-2
Hypothetical protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
 
  
 0.897
CKO_02236
Hypothetical protein; KEGG: ecs:ECs0953 1.5e-128 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG3023 Negative regulator of beta-lactamase expression.
 
    
 0.889
CKO_00358
Hypothetical protein; KEGG: ece:Z3694 2.5e-222 putative PTS enzyme II K02809:K02810; COG: COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; Psort location: CytoplasmicMembrane, score:10.00.
  
  
 0.808
CKO_00361
Hypothetical protein; KEGG cbu:CBU_1296 0.0063 NAD+ kinase K00858; Belongs to the UPF0319 family.
       0.752
murQ
Hypothetical protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
 
  
 0.553
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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