close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_00484Hypothetical protein; KEGG: sdy:SDY_2500 2.5e-55 folX; D-erythro-7,8-dihydroneopterin tri P epimerase K07589; COG: COG1539 Dihydroneopterin aldolase; Psort location: Cytoplasmic, score:8.96. (120 aa)    
Predicted Functional Partners:
folE
Hypothetical protein; KEGG: ssn:SSO_2209 4.1e-110 folE; GTP cyclohydrolase I K01495; COG: COG0302 GTP cyclohydrolase I.
 
 
 0.989
folE2
Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
 
  
 0.927
CKO_04120
Hypothetical protein; KEGG: sec:SC2880 4.7e-63 ptpS; putative synthase K01737; COG: COG0720 6-pyruvoyl-tetrahydropterin synthase; Psort location: Cytoplasmic, score:8.96.
    
 0.919
CKO_02788
Hypothetical protein; KEGG: sbo:SBO_0278 8.9e-227 phoA; alkaline phosphatase K01077; COG: COG1785 Alkaline phosphatase; Psort location: Periplasmic, score:10.00; Belongs to the alkaline phosphatase family.
  
  
  0.915
CKO_03227
Hypothetical protein; KEGG: stm:STM0183 1.9e-75 folK; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950; COG: COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
 
  
 0.903
CKO_01096
Hypothetical protein; KEGG: ecc:c2279 3.9e-66 ntpA; dATP pyrophosphohydrolase K08310; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: Cytoplasmic, score:8.96.
    
  0.901
CKO_04578
Hypothetical protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
  
 0.898
CKO_00483
KEGG: ava:Ava_0206 8.6e-55 hypothetical protein; COG: COG1090 Predicted nucleoside-diphosphate sugar epimerase.
       0.755
folM
Hypothetical protein; Catalyzes the reduction of dihydromonapterin to tetrahydromonapterin. Also has lower activity with dihydrofolate.
 
   
 0.660
CKO_00482
Hypothetical protein; KEGG: bca:BCE_1955 1.8e-13 acetyltransferase, GNAT family K00676; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.
       0.642
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: medium (50%) [HD]