close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_00486Hypothetical protein; KEGG: eci:UTI89_C2584 3.9e-82 yfcE; hypothetical protein; COG: COG0622 Predicted phosphoesterase. (183 aa)    
Predicted Functional Partners:
CKO_04330
Hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.868
CKO_00487
Hypothetical protein; KEGG: ssn:SSO_2356 8.5e-87 putative regulator; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: Cytoplasmic, score:8.96.
  
    0.710
CKO_00485
Hypothetical protein; KEGG: eci:UTI89_C2585 1.9e-89 yfcF; hypothetical protein K00799; COG: COG0625 Glutathione S-transferase; Psort location: Cytoplasmic, score:8.96.
       0.644
CKO_00636
Hypothetical protein; Serine hydrolase involved in the detoxification of formaldehyde.
  
  
 0.556
CKO_02033
Hypothetical protein; COG: NOG09737 non supervised orthologous group; Psort location: CytoplasmicMembrane, score:9.46.
  
     0.510
CKO_00484
Hypothetical protein; KEGG: sdy:SDY_2500 2.5e-55 folX; D-erythro-7,8-dihydroneopterin tri P epimerase K07589; COG: COG1539 Dihydroneopterin aldolase; Psort location: Cytoplasmic, score:8.96.
  
    0.505
CKO_00483
KEGG: ava:Ava_0206 8.6e-55 hypothetical protein; COG: COG1090 Predicted nucleoside-diphosphate sugar epimerase.
       0.475
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: low (18%) [HD]