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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menFHypothetical protein; Catalyzes the conversion of chorismate to isochorismate. (408 aa)    
Predicted Functional Partners:
menD
Hypothetical protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
 
 0.998
CKO_02566
Hypothetical protein; KEGG: spt:SPA2137 1.4e-143 entB; isochorismatase K01252; COG: COG3433 Aryl carrier domain; Psort location: Cytoplasmic, score:8.96.
  
 
 0.998
trpD
Hypothetical protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.953
CKO_02575
Hypothetical protein; KEGG: stm:STM0588 0. entF; enterobactin synthetase, component F (nonribosomal peptide synthetase) K02364; COG: COG3319 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases; Psort location: CytoplasmicMembrane, score:8.46.
  
  
 0.941
CKO_00916
Hypothetical protein; KEGG: eci:UTI89_C2178 7.5e-230 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96.
  
  
0.933
CKO_01253
Hypothetical protein; KEGG: eci:UTI89_C2178 5.3e-229 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96.
  
  
0.933
menH
Hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
 
  
 0.932
aroC
Hypothetical protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.926
CKO_02568
Hypothetical protein; KEGG: stm:STM0595 3.5e-184 entC; isochorismate synthetase, enterochelin biosynthesis K02361; COG: COG1169 Isochorismate synthase.
  
  
 
0.926
aroE
Hypothetical protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
  
 0.915
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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