| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKO_00539 | CKO_00540 | CKO_00539 | CKO_00540 | Hypothetical protein; KEGG: ype:YPO3116 1.4e-08 ddhD, ascD, rfbI; CDP-6-deoxy-delta-3,4-glucoseen reductase K00523; COG: COG0633 Ferredoxin; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: stm:STM2278 2.3e-196 nrdB; ribonucleoside-diphosphate reductase 1, beta subunit K00526; COG: COG0208 Ribonucleotide reductase, beta subunit; Psort location: Cytoplasmic, score:8.96. | 0.979 |
| CKO_00539 | CKO_00541 | CKO_00539 | CKO_00541 | Hypothetical protein; KEGG: ype:YPO3116 1.4e-08 ddhD, ascD, rfbI; CDP-6-deoxy-delta-3,4-glucoseen reductase K00523; COG: COG0633 Ferredoxin; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.928 |
| CKO_00539 | CKO_04025 | CKO_00539 | CKO_04025 | Hypothetical protein; KEGG: ype:YPO3116 1.4e-08 ddhD, ascD, rfbI; CDP-6-deoxy-delta-3,4-glucoseen reductase K00523; COG: COG0633 Ferredoxin; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.493 |
| CKO_00540 | CKO_00539 | CKO_00540 | CKO_00539 | Hypothetical protein; KEGG: stm:STM2278 2.3e-196 nrdB; ribonucleoside-diphosphate reductase 1, beta subunit K00526; COG: COG0208 Ribonucleotide reductase, beta subunit; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: ype:YPO3116 1.4e-08 ddhD, ascD, rfbI; CDP-6-deoxy-delta-3,4-glucoseen reductase K00523; COG: COG0633 Ferredoxin; Psort location: Cytoplasmic, score:8.96. | 0.979 |
| CKO_00540 | CKO_00541 | CKO_00540 | CKO_00541 | Hypothetical protein; KEGG: stm:STM2278 2.3e-196 nrdB; ribonucleoside-diphosphate reductase 1, beta subunit K00526; COG: COG0208 Ribonucleotide reductase, beta subunit; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.999 |
| CKO_00540 | CKO_01110 | CKO_00540 | CKO_01110 | Hypothetical protein; KEGG: stm:STM2278 2.3e-196 nrdB; ribonucleoside-diphosphate reductase 1, beta subunit K00526; COG: COG0208 Ribonucleotide reductase, beta subunit; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: spt:SPA0981 2.6e-243 pykA; pyruvate kinase A K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score:8.96. | 0.909 |
| CKO_00540 | CKO_04025 | CKO_00540 | CKO_04025 | Hypothetical protein; KEGG: stm:STM2278 2.3e-196 nrdB; ribonucleoside-diphosphate reductase 1, beta subunit K00526; COG: COG0208 Ribonucleotide reductase, beta subunit; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.904 |
| CKO_00540 | adk | CKO_00540 | CKO_02675 | Hypothetical protein; KEGG: stm:STM2278 2.3e-196 nrdB; ribonucleoside-diphosphate reductase 1, beta subunit K00526; COG: COG0208 Ribonucleotide reductase, beta subunit; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.921 |
| CKO_00540 | cmk | CKO_00540 | CKO_02163 | Hypothetical protein; KEGG: stm:STM2278 2.3e-196 nrdB; ribonucleoside-diphosphate reductase 1, beta subunit K00526; COG: COG0208 Ribonucleotide reductase, beta subunit; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: eco:b0910 1.4e-111 cmk, mssA, ycaF, ycaG; cytidine monophosphate (CMP) kinase K00945; COG: COG0283 Cytidylate kinase. | 0.923 |
| CKO_00540 | gmk | CKO_00540 | CKO_05105 | Hypothetical protein; KEGG: stm:STM2278 2.3e-196 nrdB; ribonucleoside-diphosphate reductase 1, beta subunit K00526; COG: COG0208 Ribonucleotide reductase, beta subunit; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Essential for recycling GMP and indirectly, cGMP. | 0.907 |
| CKO_00540 | ndk | CKO_00540 | CKO_00265 | Hypothetical protein; KEGG: stm:STM2278 2.3e-196 nrdB; ribonucleoside-diphosphate reductase 1, beta subunit K00526; COG: COG0208 Ribonucleotide reductase, beta subunit; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.920 |
| CKO_00540 | tmk | CKO_00540 | CKO_01960 | Hypothetical protein; KEGG: stm:STM2278 2.3e-196 nrdB; ribonucleoside-diphosphate reductase 1, beta subunit K00526; COG: COG0208 Ribonucleotide reductase, beta subunit; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.922 |
| CKO_00541 | CKO_00539 | CKO_00541 | CKO_00539 | Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypothetical protein; KEGG: ype:YPO3116 1.4e-08 ddhD, ascD, rfbI; CDP-6-deoxy-delta-3,4-glucoseen reductase K00523; COG: COG0633 Ferredoxin; Psort location: Cytoplasmic, score:8.96. | 0.928 |
| CKO_00541 | CKO_00540 | CKO_00541 | CKO_00540 | Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypothetical protein; KEGG: stm:STM2278 2.3e-196 nrdB; ribonucleoside-diphosphate reductase 1, beta subunit K00526; COG: COG0208 Ribonucleotide reductase, beta subunit; Psort location: Cytoplasmic, score:8.96. | 0.999 |
| CKO_00541 | CKO_01110 | CKO_00541 | CKO_01110 | Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypothetical protein; KEGG: spt:SPA0981 2.6e-243 pykA; pyruvate kinase A K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score:8.96. | 0.905 |
| CKO_00541 | CKO_04025 | CKO_00541 | CKO_04025 | Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.994 |
| CKO_00541 | CKO_04323 | CKO_00541 | CKO_04323 | Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypothetical protein; COG: COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. | 0.977 |
| CKO_00541 | adk | CKO_00541 | CKO_02675 | Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypothetical protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.921 |
| CKO_00541 | cmk | CKO_00541 | CKO_02163 | Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypothetical protein; KEGG: eco:b0910 1.4e-111 cmk, mssA, ycaF, ycaG; cytidine monophosphate (CMP) kinase K00945; COG: COG0283 Cytidylate kinase. | 0.925 |
| CKO_00541 | gmk | CKO_00541 | CKO_05105 | Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypothetical protein; Essential for recycling GMP and indirectly, cGMP. | 0.920 |