STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_00561Hypothetical protein; KEGG: sfx:S2427 1.7e-159 ada; O6-methylguanine-DNA methyltransferase; transcription activator/repressor K00567; COG: COG0350 Methylated DNA-protein cysteine methyltransferase. (359 aa)    
Predicted Functional Partners:
CKO_00562
Hypothetical protein; COG: COG3145 Alkylated DNA repair protein.
 
  
 0.905
CKO_00710
Hypothetical protein; KEGG: stm:STM2124 3.3e-124 alkA; 3-methyl-adenine DNA glycosylase II K01247; COG: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; Psort location: Cytoplasmic, score:8.96.
 
  
 0.883
rpoS
Hypothetical protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
   
   0.769
rpoD
Hypothetical protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
   0.769
rpoH
Hypothetical protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
   
   0.769
CKO_00559
Hypothetical protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.
       0.630
dinB
Hypothetical protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
  
 0.618
CKO_01410
Hypothetical protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
  
0.580
CKO_00563
Hypothetical protein; KEGG: reh:H16_B1682 8.0e-91 ABC-type transporter, ATPase and permease components: Pep3E family; COG: COG4615 ABC-type siderophore export system, fused ATPase and permease components; Psort location: CytoplasmicMembrane, score:10.00.
       0.570
CKO_02157
Hypothetical protein; KEGG: xac:XAC1087 0.0012 gloB; hydroxyacylglutathione hydrolase K01069; COG: COG0658 Predicted membrane metal-binding protein; Psort location: CytoplasmicMembrane, score:10.00.
     
 0.550
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.