Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
mqoHypothetical protein; KEGG: eci:UTI89_C2490 3.3e-259 mqo; malate dehydrogenase K00116; COG: COG0579 Predicted dehydrogenase. (553 aa)    
Predicted Functional Partners:
fumC
Hypothetical protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
    
 0.943
mdh
Hypothetical protein; Catalyzes the reversible oxidation of malate to oxaloacetate.
    
 0.938
CKO_00332
Hypothetical protein; KEGG: sty:STY2709 0. maeB; NADP-dependent malate dehydrogenase (decarboxylating) K00029; COG: COG0280 Phosphotransacetylase.
    
 0.935
ppc
Hypothetical protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.935
maeA
Hypothetical protein; KEGG: sfx:S1879 2.9e-292 sfcA; NAD-linked malate dehydrogenase (malic enzyme) K00027; COG: COG0281 Malic enzyme; Belongs to the malic enzymes family.
    
 0.929
pckA
Hypothetical protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
    
 0.929
CKO_02439
Hypothetical protein; KEGG: sec:SC0736 1.7e-225 gltA; citrate synthase K01647; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score:9.26.
    
 0.927
CKO_02829
Hypothetical protein; KEGG: ecp:ECP_0408 9.0e-202 2-methylcitrate synthase K01659; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score:9.26.
    
 0.927
CKO_03906
Hypothetical protein; KEGG: stm:STM4183 5.2e-277 aceB; malate synthase A K01638; COG: COG2225 Malate synthase; Psort location: Cytoplasmic, score:9.97.
   
 
 0.926
CKO_01623
Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
   
 
 0.925
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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