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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_00657COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00. (478 aa)    
Predicted Functional Partners:
macB
Hypothetical protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.873
CKO_04034
Hypothetical protein; COG: COG1566 Multidrug resistance efflux pump.
 
 
 0.857
CKO_04677
COG: COG0845 Membrane-fusion protein; Psort location: CytoplasmicMembrane, score:8.60; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.695
CKO_02837
COG: COG0845 Membrane-fusion protein; Psort location: CytoplasmicMembrane, score:8.02; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.685
CKO_02688
Hypothetical protein; KEGG: saz:Sama_0326 0.0047 phosphopantothenoylcysteine decarboxylase, phosphopantothenate--cysteine ligase K01598:K01922; COG: COG0845 Membrane-fusion protein; Psort location: CytoplasmicMembrane, score:8.60.
 
 
 0.675
aaeA
Hypothetical protein; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.658
CKO_02332
COG: COG0845 Membrane-fusion protein; Psort location: CytoplasmicMembrane, score:8.60.
 
 
 0.639
CKO_01656
Hypothetical protein; KEGG: ece:Z0125 0.0037 aceF; pyruvate dehydrogenase (dihydrolipoyltransacetylase component) K00627; COG: COG1566 Multidrug resistance efflux pump; Psort location: CytoplasmicMembrane, score:8.02; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.622
CKO_05051
Hypothetical protein; COG: COG1566 Multidrug resistance efflux pump.
 
 
 0.622
CKO_03447
Hypothetical protein; COG: COG1566 Multidrug resistance efflux pump.
 
 
 0.614
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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