STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdtACOG: COG0845 Membrane-fusion protein; Psort location: CytoplasmicMembrane, score:8.02; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (433 aa)    
Predicted Functional Partners:
mdtC
Hypothetical protein; KEGG: eci:UTI89_C2351 0. yegO; hypothetical protein YegO K07789; COG: COG0841 Cation/multidrug efflux pump; Psort location: CytoplasmicMembrane, score:10.00; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
 
 
 0.996
mdtB
Hypothetical protein; KEGG: eci:UTI89_C2351 5.6e-257 yegO; hypothetical protein YegO K07789; COG: COG0841 Cation/multidrug efflux pump; Psort location: CytoplasmicMembrane, score:10.00; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
 
 
 0.996
CKO_00703
Hypothetical protein; KEGG: sec:SC2132 4.3e-227 baeS, baeR; sensory kinase in two-component regulatoyr system wtih BaeR K07642; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score:9.82.
  
  
 0.968
macB
Hypothetical protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.965
CKO_00319
Hypothetical protein; KEGG: eci:UTI89_C2351 2.5e-112 yegO; hypothetical protein YegO K07789; COG: COG0841 Cation/multidrug efflux pump; Psort location: CytoplasmicMembrane, score:10.00.
 
 
 0.919
mdtD
Hypothetical protein; KEGG: sgl:SG1466 6.1e-08 dethiobiotin synthase K01935; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score:10.00.
 
  
 0.874
CKO_01768
Hypothetical protein; COG: COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein; Psort location: Periplasmic, score:10.00.
   
  
 0.864
CKO_01120
COG: COG2979 Uncharacterized protein conserved in bacteria.
   
    0.857
CKO_00702
Hypothetical protein; KEGG: eci:UTI89_C2354 1.7e-122 baeR; transcriptional response regulatory protein BaeR K07664; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score:9.97.
  
  
 0.855
CKO_04679
Hypothetical protein; COG: NOG14133 non supervised orthologous group.
   
    0.816
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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