STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcdHypothetical protein; Catalyzes the deamination of dCTP to dUTP. (193 aa)    
Predicted Functional Partners:
ndk
Hypothetical protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.937
dut
Hypothetical protein; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
    
 0.935
CKO_04136
Hypothetical protein; KEGG: pha:PSHAa0740 1.5e-59 mazG; nucleoside triphosphate pyrophosphohydrolase, non-specific K02428; COG: COG1694 Predicted pyrophosphatase; Psort location: Cytoplasmic, score:8.96.
     
 0.925
pyrG
Hypothetical protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
 
 0.924
CKO_03580
Hypothetical protein; KEGG: spt:SPA4252 0. nrdD; anaerobic ribonucleoside-triphosphate reductase K00527; COG: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score:8.96.
    
 0.904
CKO_00717
COG: COG2982 Uncharacterized protein involved in outer membrane biogenesis.
       0.739
CKO_00718
Hypothetical protein.
       0.690
CKO_00541
Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
   
 0.682
CKO_00715
Hypothetical protein; KEGG: sty:STY2335 1.6e-53 udk; uridine kinase K00876; COG: COG0572 Uridine kinase; Psort location: Cytoplasmic, score:8.96.
     
 0.618
CKO_00104
COG: COG3085 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.96.
  
     0.608
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.