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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_00773Hypothetical protein; KEGG: ecp:ECP_2055 3.4e-250 exodeoxyribonuclease I K01141; COG: COG2925 Exonuclease I; Psort location: Cytoplasmic, score:8.96. (474 aa)    
Predicted Functional Partners:
CKO_03842
Hypothetical protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
    
 
 0.676
CKO_04254
Hypothetical protein; KEGG: ecc:c3472 1.2e-295 recJ; single-stranded-DNA-specific exonuclease RecJ K07462; COG: COG0608 Single-stranded DNA-specific exonuclease; Psort location: Cytoplasmic, score:8.96.
    
 
 0.666
rdgC
Hypothetical protein; May be involved in recombination; Belongs to the RdgC family.
  
     0.590
CKO_00774
Hypothetical protein; KEGG: stm:STM2062 5.8e-191 dacD; DD-carboxypeptidase, penicillin-binding protein 6b K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Psort location: CytoplasmicMembrane, score:8.60; Belongs to the peptidase S11 family.
       0.544
rnhA
Hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 
 0.462
recB
Hypothetical protein; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme [...]
 
   
 0.418
recC
Hypothetical protein; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme [...]
  
   
 0.412
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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