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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
amnHypothetical protein; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (484 aa)    
Predicted Functional Partners:
apt
Hypothetical protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.924
CKO_04151
Hypothetical protein; KEGG: hch:HCH_00651 4.5e-129 predicted Rossmann fold nucleotide-binding protein K00052; COG: COG1611 Predicted Rossmann fold nucleotide-binding protein; Psort location: Cytoplasmic, score:8.96.
   
 
 0.914
CKO_03418
Hypothetical protein; KEGG: spt:SPA4373 3.0e-107 yjjG; hypothetical protein K08723; COG: COG1011 Predicted hydrolase (HAD superfamily).
  
 
  0.904
CKO_04822
Hypothetical protein; KEGG: rso:RSc2880 1.3e-07 gph, RS00222; probable phosphoglycolate phosphatase protein K01091; COG: COG1011 Predicted hydrolase (HAD superfamily); Psort location: Cytoplasmic, score:8.96.
  
 
  0.904
deoD
Hypothetical protein; KEGG: sty:STY4921 3.0e-123 deoD, pup; purine nucleoside phosphorylase K03784; COG: COG0813 Purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score:8.96.
   
 
 0.902
CKO_01840
Hypothetical protein; KEGG: ssn:SSO_1149 2.9e-237 purB; adenylosuccinate lyase K01756; COG: COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
  0.900
CKO_02669
Hypothetical protein; KEGG: sec:SC0536 3.0e-281 ushA; UDP-sugar hydrolase 5'-nucleotidase K01081:K08077; COG: COG0737 5-nucleotidase/2,3-cyclic phosphodiesterase and related esterases; Psort location: Periplasmic, score:10.00; Belongs to the 5'-nucleotidase family.
     
  0.900
adk
Hypothetical protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
  0.900
ppnP
Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.900
surE
Hypothetical protein; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
     
 0.900
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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