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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliTHypothetical protein; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus. (120 aa)    
Predicted Functional Partners:
CKO_01014
Hypothetical protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
     0.910
CKO_01013
Hypothetical protein; COG: COG1516 Flagellin-specific chaperone FliS.
       0.800
CKO_01989
Hypothetical protein; COG: COG3418 Flagellar biosynthesis/type III secretory pathway chaperone.
  
     0.703
CKO_01003
Hypothetical protein; COG: COG1317 Flagellar biosynthesis/type III secretory pathway protein.
  
     0.647
CKO_05112
Hypothetical protein; COG: NOG06061 non supervised orthologous group.
  
     0.645
CKO_01011
Hypothetical protein; KEGG: ecj:JW1912 4.7e-260 amyA; cytoplasmic alpha-amylase K01176; COG: COG0366 Glycosidases; Psort location: Cytoplasmic, score:9.97.
       0.627
CKO_01001
Hypothetical protein; Flagellar protein that affects chemotactic events. Belongs to the FliJ family.
  
     0.626
CKO_03760
Hypothetical protein; KEGG: reh:H16_A0378 0.0039 predicted GTPase K01529; COG: COG0699 Predicted GTPases (dynamin-related).
  
     0.620
CKO_02328
COG: COG3539 P pilus assembly protein, pilin FimA; Psort location: Extracellular, score:9.72.
  
     0.580
CKO_01485
Hypothetical protein; KEGG: mag:amb3277 9.8e-09 RTX toxins and related Ca2+-binding protein K00754; COG: NOG35976 non supervised orthologous group.
  
     0.577
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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