STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_01049Hypothetical protein; KEGG: lic:LIC11685 1.1e-15 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis K03152; COG: COG0693 Putative intracellular protease/amidase; Psort location: Cytoplasmic, score:8.96. (185 aa)    
Predicted Functional Partners:
CKO_02737
Hypothetical protein; KEGG: eci:UTI89_C0447 2.6e-94 thiJ; 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme K03152; COG: COG0693 Putative intracellular protease/amidase.
 
    
0.672
dnaJ
Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dna [...]
  
 
 0.660
rplM
Hypothetical protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.645
CKO_01658
Hypothetical protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 
 0.636
rplE
Hypothetical protein; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
   
   0.634
rpsS
Hypothetical protein; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
   0.632
rpsJ
Hypothetical protein; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
   0.630
rpmA
COG: COG0211 Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
   
   0.628
rpsB
COG: COG0052 Ribosomal protein S2; Psort location: Cytoplasmic, score:8.96; Belongs to the universal ribosomal protein uS2 family.
   
   0.627
CKO_03259
Hypothetical protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
   0.620
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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