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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycgRHypothetical protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility. (244 aa)    
Predicted Functional Partners:
CKO_00521
Hypothetical protein; KEGG: stm:STM2314 1.5e-162 putative chemotaxis signal transduction protein K03415; COG: COG0784 FOG: CheY-like receiver; Psort location: Cytoplasmic, score:8.96.
 
  
 0.841
CKO_01988
Hypothetical protein; COG: COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor).
 
  
 0.827
CKO_01013
Hypothetical protein; COG: COG1516 Flagellin-specific chaperone FliS.
 
  
 0.826
CKO_04967
Hypothetical protein; KEGG: shn:Shewana3_3829 0.00021 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG2200 FOG: EAL domain; Psort location: Cytoplasmic, score:8.96.
  
  
 0.795
CKO_01014
Hypothetical protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
    0.749
CKO_01989
Hypothetical protein; COG: COG3418 Flagellar biosynthesis/type III secretory pathway chaperone.
 
  
 0.741
CKO_01059
COG: COG1360 Flagellar motor protein.
 
 
 0.734
CKO_03890
Hypothetical protein; COG: NOG06220 non supervised orthologous group.
  
     0.733
CKO_02863
Hypothetical protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
    0.709
CKO_02102
COG: COG3110 Uncharacterized protein conserved in bacteria; Belongs to the UPF0319 family.
  
     0.689
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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