| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKO_01253 | CKO_02566 | CKO_01253 | CKO_02566 | Hypothetical protein; KEGG: eci:UTI89_C2178 5.3e-229 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: spt:SPA2137 1.4e-143 entB; isochorismatase K01252; COG: COG3433 Aryl carrier domain; Psort location: Cytoplasmic, score:8.96. | 0.989 |
| CKO_01253 | CKO_02568 | CKO_01253 | CKO_02568 | Hypothetical protein; KEGG: eci:UTI89_C2178 5.3e-229 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: stm:STM0595 3.5e-184 entC; isochorismate synthetase, enterochelin biosynthesis K02361; COG: COG1169 Isochorismate synthase. | 0.930 |
| CKO_01253 | CKO_04782 | CKO_01253 | CKO_04782 | Hypothetical protein; KEGG: eci:UTI89_C2178 5.3e-229 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: spt:SPA3335 4.3e-92 pabA; para-aminobenzoate synthase, glutamine amidotransferase component II K01664; COG: COG0512 Anthranilate/para-aminobenzoate synthases component II. | 0.983 |
| CKO_01253 | aroC | CKO_01253 | CKO_00456 | Hypothetical protein; KEGG: eci:UTI89_C2178 5.3e-229 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.930 |
| CKO_01253 | aroE | CKO_01253 | CKO_04694 | Hypothetical protein; KEGG: eci:UTI89_C2178 5.3e-229 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.932 |
| CKO_01253 | menF | CKO_01253 | CKO_00525 | Hypothetical protein; KEGG: eci:UTI89_C2178 5.3e-229 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Catalyzes the conversion of chorismate to isochorismate. | 0.933 |
| CKO_01253 | trpA | CKO_01253 | CKO_01336 | Hypothetical protein; KEGG: eci:UTI89_C2178 5.3e-229 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.963 |
| CKO_01253 | trpB | CKO_01253 | CKO_01337 | Hypothetical protein; KEGG: eci:UTI89_C2178 5.3e-229 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.961 |
| CKO_01253 | trpC | CKO_01253 | CKO_01338 | Hypothetical protein; KEGG: eci:UTI89_C2178 5.3e-229 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: sfx:S1351 2.8e-214 trpC; N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase K01609:K01817; COG: COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.996 |
| CKO_01253 | trpD | CKO_01253 | CKO_01339 | Hypothetical protein; KEGG: eci:UTI89_C2178 5.3e-229 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
| CKO_02566 | CKO_01253 | CKO_02566 | CKO_01253 | Hypothetical protein; KEGG: spt:SPA2137 1.4e-143 entB; isochorismatase K01252; COG: COG3433 Aryl carrier domain; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: eci:UTI89_C2178 5.3e-229 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96. | 0.989 |
| CKO_02566 | CKO_02568 | CKO_02566 | CKO_02568 | Hypothetical protein; KEGG: spt:SPA2137 1.4e-143 entB; isochorismatase K01252; COG: COG3433 Aryl carrier domain; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: stm:STM0595 3.5e-184 entC; isochorismate synthetase, enterochelin biosynthesis K02361; COG: COG1169 Isochorismate synthase. | 0.999 |
| CKO_02566 | menF | CKO_02566 | CKO_00525 | Hypothetical protein; KEGG: spt:SPA2137 1.4e-143 entB; isochorismatase K01252; COG: COG3433 Aryl carrier domain; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Catalyzes the conversion of chorismate to isochorismate. | 0.998 |
| CKO_02566 | trpD | CKO_02566 | CKO_01339 | Hypothetical protein; KEGG: spt:SPA2137 1.4e-143 entB; isochorismatase K01252; COG: COG3433 Aryl carrier domain; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.520 |
| CKO_02568 | CKO_01253 | CKO_02568 | CKO_01253 | Hypothetical protein; KEGG: stm:STM0595 3.5e-184 entC; isochorismate synthetase, enterochelin biosynthesis K02361; COG: COG1169 Isochorismate synthase. | Hypothetical protein; KEGG: eci:UTI89_C2178 5.3e-229 ybtS; putative salicylate synthetase K04781; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96. | 0.930 |
| CKO_02568 | CKO_02566 | CKO_02568 | CKO_02566 | Hypothetical protein; KEGG: stm:STM0595 3.5e-184 entC; isochorismate synthetase, enterochelin biosynthesis K02361; COG: COG1169 Isochorismate synthase. | Hypothetical protein; KEGG: spt:SPA2137 1.4e-143 entB; isochorismatase K01252; COG: COG3433 Aryl carrier domain; Psort location: Cytoplasmic, score:8.96. | 0.999 |
| CKO_02568 | CKO_04782 | CKO_02568 | CKO_04782 | Hypothetical protein; KEGG: stm:STM0595 3.5e-184 entC; isochorismate synthetase, enterochelin biosynthesis K02361; COG: COG1169 Isochorismate synthase. | Hypothetical protein; KEGG: spt:SPA3335 4.3e-92 pabA; para-aminobenzoate synthase, glutamine amidotransferase component II K01664; COG: COG0512 Anthranilate/para-aminobenzoate synthases component II. | 0.631 |
| CKO_02568 | aroC | CKO_02568 | CKO_00456 | Hypothetical protein; KEGG: stm:STM0595 3.5e-184 entC; isochorismate synthetase, enterochelin biosynthesis K02361; COG: COG1169 Isochorismate synthase. | Hypothetical protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.889 |
| CKO_02568 | aroE | CKO_02568 | CKO_04694 | Hypothetical protein; KEGG: stm:STM0595 3.5e-184 entC; isochorismate synthetase, enterochelin biosynthesis K02361; COG: COG1169 Isochorismate synthase. | Hypothetical protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.878 |
| CKO_02568 | menF | CKO_02568 | CKO_00525 | Hypothetical protein; KEGG: stm:STM0595 3.5e-184 entC; isochorismate synthetase, enterochelin biosynthesis K02361; COG: COG1169 Isochorismate synthase. | Hypothetical protein; Catalyzes the conversion of chorismate to isochorismate. | 0.926 |