close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_01340Hypothetical protein; KEGG: stm:STM1723 1.2e-252 trpE; anthranilate synthase, component I K01657; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score:8.96. (524 aa)    
Predicted Functional Partners:
trpC
Hypothetical protein; KEGG: sfx:S1351 2.8e-214 trpC; N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase K01609:K01817; COG: COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
 
 0.999
trpD
Hypothetical protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 0.999
CKO_04782
Hypothetical protein; KEGG: spt:SPA3335 4.3e-92 pabA; para-aminobenzoate synthase, glutamine amidotransferase component II K01664; COG: COG0512 Anthranilate/para-aminobenzoate synthases component II.
 0.999
trpA
Hypothetical protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.992
trpB
Hypothetical protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.992
aroC
Hypothetical protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.972
CKO_03919
Hypothetical protein; KEGG: ecj:JW2580 5.1e-192 pheA; fused chorismate mutase P and prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score:9.97.
 
 
 0.964
CKO_03920
Hypothetical protein; KEGG: sty:STY2856 6.9e-188 tyrA; prephenate dehydrogenase / chorismate mutase K04092:K04517; COG: COG0287 Prephenate dehydrogenase; Psort location: Cytoplasmic, score:8.96.
 
 
 0.959
CKO_02322
Hypothetical protein; KEGG: rso:RSc0378 1.5e-50 trpD3, RS03346; putative anthranilate phosphoribosyltransferase protein K00766; COG: COG0547 Anthranilate phosphoribosyltransferase.
 
 
 0.901
CKO_02566
Hypothetical protein; KEGG: spt:SPA2137 1.4e-143 entB; isochorismatase K01252; COG: COG3433 Aryl carrier domain; Psort location: Cytoplasmic, score:8.96.
  
  
 0.895
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.