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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_01343Hypothetical protein; KEGG: eci:UTI89_C1537 8.4e-151 yciL; hypothetical protein YciL K06178; COG: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Psort location: Cytoplasmic, score:8.96; Belongs to the pseudouridine synthase RsuA family. (291 aa)    
Predicted Functional Partners:
der
Hypothetical protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.872
CKO_01777
Hypothetical protein; KEGG: sdy:SDY_1527 3.9e-137 xthA; exonuclease III K01142; COG: COG0708 Exonuclease III; Psort location: Cytoplasmic, score:9.97.
  
    0.822
cmk
Hypothetical protein; KEGG: eco:b0910 1.4e-111 cmk, mssA, ycaF, ycaG; cytidine monophosphate (CMP) kinase K00945; COG: COG0283 Cytidylate kinase.
  
 0.809
rlmL
Hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.
  
 
 0.651
CKO_01342
Hypothetical protein; COG: COG0009 Putative translation factor (SUA5); Psort location: Cytoplasmic, score:8.96; Belongs to the SUA5 family.
  
  
 0.602
CKO_01341
Hypothetical protein; KEGG: reh:H16_A1200 1.4e-40 predicted metal-dependent phosphoesterase (PHP family); COG: COG0613 Predicted metal-dependent phosphoesterases (PHP family); Psort location: Cytoplasmic, score:8.96.
       0.580
rsmG
Hypothetical protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
  
     0.547
trmB
Hypothetical protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
 
  
 0.538
era
Hypothetical protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
 
    0.524
rlmN
Hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
 
  
 0.520
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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