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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_01352Hypothetical protein; KEGG: shn:Shewana3_3435 2.7e-12 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score:9.97; Belongs to the LysR transcriptional regulatory family. (324 aa)    
Predicted Functional Partners:
CKO_04651
Hypothetical protein; KEGG: shn:Shewana3_3435 8.8e-10 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score:9.26; Belongs to the LysR transcriptional regulatory family.
  
     0.599
topA
Hypothetical protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...]
 
   
 0.581
CKO_01353
Hypothetical protein.
       0.570
CKO_05115
Hypothetical protein; KEGG: shn:Shewana3_3435 4.0e-05 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.489
CKO_00434
Hypothetical protein; KEGG: shn:Shewana3_3435 3.5e-11 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score:9.97; Belongs to the LysR transcriptional regulatory family.
  
     0.472
hdfR
Hypothetical protein; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
  
     0.463
CKO_01179
Hypothetical protein; KEGG: shn:Shewana3_3435 7.6e-07 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score:9.97; Belongs to the LysR transcriptional regulatory family.
  
     0.447
CKO_04450
Hypothetical protein; KEGG: shn:Shewana3_3435 5.4e-08 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score:9.97; Belongs to the LysR transcriptional regulatory family.
  
     0.440
CKO_03356
Hypothetical protein; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score:9.26; Belongs to the LysR transcriptional regulatory family.
  
     0.420
CKO_00769
Hypothetical protein; KEGG: shn:Shewana3_3435 0.0011 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.419
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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