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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnbHypothetical protein; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction. (644 aa)    
Predicted Functional Partners:
rne
Hypothetical protein; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.
     
 0.615
CKO_01374
Hypothetical protein; COG: COG2128 Uncharacterized conserved protein.
       0.609
rph
Hypothetical protein; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
     
 0.603
rnd
Hypothetical protein; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.
     
 0.602
rnpA
Hypothetical protein; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
     
  0.499
CKO_02987
COG: COG3068 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.96.
  
     0.492
CKO_01371
Hypothetical protein; KEGG: shn:Shewana3_3829 4.8e-85 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG2199 FOG: GGDEF domain.
       0.466
CKO_04019
Hypothetical protein; COG: COG4575 Uncharacterized conserved protein.
  
     0.450
CKO_04147
Hypothetical protein; KEGG: shn:Shewana3_2825 3.5e-10 dTDP-4-dehydrorhamnose 3,5-epimerase K01790; COG: COG3098 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.96.
  
     0.446
CKO_04501
COG: COG5393 Predicted membrane protein.
  
     0.446
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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