Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CKO_01374Hypothetical protein; COG: COG2128 Uncharacterized conserved protein. (385 aa)    
Predicted Functional Partners:
cysJ
Hypothetical protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
   
  
 0.911
cysN
Hypothetical protein; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
   
    0.903
CKO_00365
Hypothetical protein; COG: COG4150 ABC-type sulfate transport system, periplasmic component; Psort location: Periplasmic, score:10.00.
   
    0.894
cysI
Hypothetical protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
   
  
 0.887
cysA
Hypothetical protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
   
    0.848
CKO_04302
Hypothetical protein; KEGG: sme:SMb21276 8.1e-27 potA; putative spermidineputrescine ABC transporter ATP-binding protein K02052; COG: COG1118 ABC-type sulfate/molybdate transport systems, ATPase component.
   
    0.848
cysD
Hypothetical protein; KEGG: ecp:ECP_2734 3.9e-162 sulfate adenylyltransferase subunit 2 K00957; COG: COG0175 3-phosphoadenosine 5-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes; Psort location: Cytoplasmic, score:8.96.
   
  
 0.836
CKO_03083
Hypothetical protein; COG: COG1613 ABC-type sulfate transport system, periplasmic component; Psort location: Periplasmic, score:10.00.
   
    0.817
cysC
Hypothetical protein; Catalyzes the synthesis of activated sulfate.
   
    0.814
cysH
Hypothetical protein; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
   
  
 0.779
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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