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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_01410Hypothetical protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (171 aa)    
Predicted Functional Partners:
CKO_04999
Hypothetical protein; KEGG: stt:t3877 7.8e-93 tag; 3-methyladenine DNA glycosylase I K01246; COG: COG2818 3-methyladenine DNA glycosylase.
   
 0.775
CKO_01411
Hypothetical protein.
       0.773
CKO_00561
Hypothetical protein; KEGG: sfx:S2427 1.7e-159 ada; O6-methylguanine-DNA methyltransferase; transcription activator/repressor K00567; COG: COG0350 Methylated DNA-protein cysteine methyltransferase.
 
  
0.580
CKO_02179
Hypothetical protein; KEGG: pha:PSHAa1714 8.0e-139 rarA; polynucleotide enzyme with nucleotide triphosphate hydrolase domain K07478; COG: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; Psort location: Cytoplasmic, score:8.96.
 
   
 0.574
CKO_00710
Hypothetical protein; KEGG: stm:STM2124 3.3e-124 alkA; 3-methyl-adenine DNA glycosylase II K01247; COG: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; Psort location: Cytoplasmic, score:8.96.
 
  
 0.538
polA
Hypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 
 
 0.525
CKO_01409
Hypothetical protein; KEGG: eci:UTI89_C3860 2.5e-08 crp; CRP-cAMP transcriptional dual regulator K00924; COG: COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; Psort location: Cytoplasmic, score:9.97.
       0.519
CKO_01405
COG: COG0589 Universal stress protein UspA and related nucleotide-binding proteins; Psort location: Cytoplasmic, score:8.96.
  
    0.504
dinB
Hypothetical protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
   
 0.489
ruvB
Hypothetical protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
 
   
 0.465
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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