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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_01423COG: COG3203 Outer membrane protein (porin); Psort location: OuterMembrane, score:10.00. (375 aa)    
Predicted Functional Partners:
CKO_01422
Hypothetical protein.
       0.773
tolB
Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
  
 
 
 0.773
zapB
Hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
  
     0.766
CKO_04637
Hypothetical protein; KEGG: eco:b3233 1.1e-63 yhcB; hypothetical protein K00424; COG: COG3105 Uncharacterized protein conserved in bacteria.
  
     0.762
CKO_04943
Hypothetical protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.
  
    0.757
CKO_03421
Hypothetical protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.756
CKO_02111
Hypothetical protein; KEGG: bte:BTH_I0426 9.3e-06 cytochrome c oxidase, subunit II K02275; COG: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; Psort location: OuterMembrane, score:10.00; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
 
 0.744
mukF
Hypothetical protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
     0.743
CKO_02105
Hypothetical protein; KEGG: eci:UTI89_C1028 0. helD; DNA helicase IV K03658; COG: COG0210 Superfamily I DNA and RNA helicases; Psort location: Cytoplasmic, score:8.96.
  
     0.733
lpoB
Hypothetical protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).
  
     0.720
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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