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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
maeAHypothetical protein; KEGG: sfx:S1879 2.9e-292 sfcA; NAD-linked malate dehydrogenase (malic enzyme) K00027; COG: COG0281 Malic enzyme; Belongs to the malic enzymes family. (565 aa)    
Predicted Functional Partners:
fumC
Hypothetical protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.951
CKO_01425
Hypothetical protein; KEGG: ecp:ECP_1403 0. probable pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.
    
 0.948
CKO_01623
Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.940
CKO_02424
Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.940
CKO_03749
Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.940
CKO_01110
Hypothetical protein; KEGG: spt:SPA0981 2.6e-243 pykA; pyruvate kinase A K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score:8.96.
  
 0.934
CKO_01709
Hypothetical protein; KEGG: stm:STM1378 2.2e-237 pykF; pyruvate kinase I (formerly F), fructose stimulated K00873; COG: COG0469 Pyruvate kinase.
  
 0.934
ldh
Hypothetical protein; Catalyzes the conversion of lactate to pyruvate.
  
 0.932
mdh
Hypothetical protein; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 0.932
CKO_03259
Hypothetical protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.928
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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