close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_01604Hypothetical protein; KEGG: sty:STY1583 2.7e-129 putative secreted protein K04775; COG: COG3591 V8-like Glu-specific endopeptidase; Belongs to the peptidase S1B family. (272 aa)    
Predicted Functional Partners:
rcsD
Hypothetical protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
  
    0.766
CKO_03177
Hypothetical protein; COG: COG4568 Transcriptional antiterminator; Psort location: Cytoplasmic, score:8.96.
  
     0.753
CKO_01619
Hypothetical protein; KEGG: spt:SPA1384 1.1e-203 rstB; two component sensor kinase K07639; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score:10.00.
  
    0.750
CKO_01625
COG: COG5339 Uncharacterized protein conserved in bacteria.
  
     0.749
CKO_00315
Hypothetical protein; COG: NOG13899 non supervised orthologous group.
  
     0.716
ftsN
Hypothetical protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
     0.683
CKO_04018
Hypothetical protein; COG: NOG09772 non supervised orthologous group.
  
     0.683
CKO_01435
Hypothetical protein; COG: NOG06225 non supervised orthologous group.
  
     0.682
rcsC
Hypothetical protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
  
    0.670
CKO_02005
Hypothetical protein; COG: NOG14214 non supervised orthologous group.
  
     0.664
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.