close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tusHypothetical protein; Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence; Belongs to the Tus family. (309 aa)    
Predicted Functional Partners:
secM
Hypothetical protein; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family.
  
   
 0.854
CKO_01952
Hypothetical protein; COG: COG5633 Predicted periplasmic lipoprotein.
  
     0.772
CKO_02304
COG: COG3637 Opacity protein and related surface antigens; Psort location: OuterMembrane, score:10.00.
  
     0.772
CKO_02690
Hypothetical protein; COG: NOG09846 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96.
  
     0.772
CKO_02005
Hypothetical protein; COG: NOG14214 non supervised orthologous group.
  
     0.771
CKO_01124
Hypothetical protein; KEGG: spt:SPA0993 1.7e-33 holE; DNA polymerase III, theta subunit K02345; COG: NOG13893 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96.
  
     0.770
aaeX
Hypothetical protein; COG: NOG13538 non supervised orthologous group.
  
     0.770
CKO_01127
Hypothetical protein; COG: NOG09766 non supervised orthologous group.
  
     0.769
CKO_01577
Hypothetical protein; COG: NOG11441 non supervised orthologous group; Belongs to the UPF0482 family.
  
     0.769
CKO_01030
Hypothetical protein; COG: NOG13894 non supervised orthologous group.
  
     0.765
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: medium (66%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.