node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CKO_00372 | CKO_01438 | CKO_00372 | CKO_01438 | Hypothetical protein; KEGG: stm:STM2435 8.1e-130 pdxK; pyridoxal-pyridoxamine kinase/hydroxymethylpyrimidine kinase K00868; COG: COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: eco:b1406 1.7e-127 ydbC; predicted oxidoreductase, NAD(P)-binding; COG: COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); Psort location: Cytoplasmic, score:8.96. | 0.920 |
CKO_00372 | pdxH | CKO_00372 | CKO_01650 | Hypothetical protein; KEGG: stm:STM2435 8.1e-130 pdxK; pyridoxal-pyridoxamine kinase/hydroxymethylpyrimidine kinase K00868; COG: COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.923 |
CKO_00372 | pdxJ | CKO_00372 | CKO_00218 | Hypothetical protein; KEGG: stm:STM2435 8.1e-130 pdxK; pyridoxal-pyridoxamine kinase/hydroxymethylpyrimidine kinase K00868; COG: COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.906 |
CKO_00372 | pdxY | CKO_00372 | CKO_01648 | Hypothetical protein; KEGG: stm:STM2435 8.1e-130 pdxK; pyridoxal-pyridoxamine kinase/hydroxymethylpyrimidine kinase K00868; COG: COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.923 |
CKO_01438 | CKO_00372 | CKO_01438 | CKO_00372 | Hypothetical protein; KEGG: eco:b1406 1.7e-127 ydbC; predicted oxidoreductase, NAD(P)-binding; COG: COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: stm:STM2435 8.1e-130 pdxK; pyridoxal-pyridoxamine kinase/hydroxymethylpyrimidine kinase K00868; COG: COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Psort location: Cytoplasmic, score:8.96. | 0.920 |
CKO_01438 | pdxH | CKO_01438 | CKO_01650 | Hypothetical protein; KEGG: eco:b1406 1.7e-127 ydbC; predicted oxidoreductase, NAD(P)-binding; COG: COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.906 |
CKO_01438 | pdxY | CKO_01438 | CKO_01648 | Hypothetical protein; KEGG: eco:b1406 1.7e-127 ydbC; predicted oxidoreductase, NAD(P)-binding; COG: COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.920 |
CKO_01651 | anmK | CKO_01651 | CKO_01652 | Hypothetical protein; COG: COG3895 Predicted periplasmic protein. | Hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.598 |
CKO_01651 | pdxH | CKO_01651 | CKO_01650 | Hypothetical protein; COG: COG3895 Predicted periplasmic protein. | Hypothetical protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.640 |
CKO_01651 | tyrS | CKO_01651 | CKO_01649 | Hypothetical protein; COG: COG3895 Predicted periplasmic protein. | Hypothetical protein; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.420 |
CKO_02042 | gcvP | CKO_02042 | CKO_04266 | Hypothetical protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.843 |
CKO_02042 | pdxH | CKO_02042 | CKO_01650 | Hypothetical protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Hypothetical protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.465 |
CKO_02042 | pdxJ | CKO_02042 | CKO_00218 | Hypothetical protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Hypothetical protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.408 |
anmK | CKO_01651 | CKO_01652 | CKO_01651 | Hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Hypothetical protein; COG: COG3895 Predicted periplasmic protein. | 0.598 |
anmK | pdxH | CKO_01652 | CKO_01650 | Hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Hypothetical protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.454 |
gcvP | CKO_02042 | CKO_04266 | CKO_02042 | Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Hypothetical protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.843 |
gcvP | pdxH | CKO_04266 | CKO_01650 | Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Hypothetical protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.555 |
pdxH | CKO_00372 | CKO_01650 | CKO_00372 | Hypothetical protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Hypothetical protein; KEGG: stm:STM2435 8.1e-130 pdxK; pyridoxal-pyridoxamine kinase/hydroxymethylpyrimidine kinase K00868; COG: COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Psort location: Cytoplasmic, score:8.96. | 0.923 |
pdxH | CKO_01438 | CKO_01650 | CKO_01438 | Hypothetical protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Hypothetical protein; KEGG: eco:b1406 1.7e-127 ydbC; predicted oxidoreductase, NAD(P)-binding; COG: COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); Psort location: Cytoplasmic, score:8.96. | 0.906 |
pdxH | CKO_01651 | CKO_01650 | CKO_01651 | Hypothetical protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Hypothetical protein; COG: COG3895 Predicted periplasmic protein. | 0.640 |