Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CKO_01656Hypothetical protein; KEGG: ece:Z0125 0.0037 aceF; pyruvate dehydrogenase (dihydrolipoyltransacetylase component) K00627; COG: COG1566 Multidrug resistance efflux pump; Psort location: CytoplasmicMembrane, score:8.02; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (289 aa)    
Predicted Functional Partners:
CKO_01657
COG: COG1289 Predicted membrane protein; Psort location: CytoplasmicMembrane, score:10.00.
 
  
 0.984
CKO_01655
Hypothetical protein; COG: NOG13888 non supervised orthologous group.
  
  
 0.958
macB
Hypothetical protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.844
CKO_02835
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.648
CKO_00657
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.637
CKO_01443
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.630
CKO_02614
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.620
slyA
Hypothetical protein; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.
 
  
 0.617
CKO_04427
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
  
 
 0.560
CKO_04035
Hypothetical protein; KEGG: sgl:SG1466 1.5e-06 dethiobiotin synthase K01935; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score:10.00.
  
 
 0.511
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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