close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_01710COG: COG4238 Murein lipoprotein. (78 aa)    
Predicted Functional Partners:
lolA
Hypothetical protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
  
 
 
 0.893
CKO_01316
COG: COG2916 DNA-binding protein H-NS; Psort location: Cytoplasmic, score:9.97; Belongs to the histone-like protein H-NS family.
  
    0.817
CKO_01329
Hypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
    
   0.799
CKO_03613
Hypothetical protein; COG: NOG17567 non supervised orthologous group.
  
     0.761
CKO_01332
Hypothetical protein; COG: NOG06197 non supervised orthologous group; Psort location: CytoplasmicMembrane, score:10.00.
  
     0.752
CKO_02691
Hypothetical protein; COG: NOG13543 non supervised orthologous group.
  
    0.750
CKO_02727
COG: COG3056 Uncharacterized lipoprotein.
  
     0.750
CKO_00558
COG: COG3203 Outer membrane protein (porin); Psort location: OuterMembrane, score:10.00; Belongs to the Gram-negative porin family.
  
  
 0.747
CKO_03675
Hypothetical protein; KEGG: rno:113960 5.0e-08 Cdc42bpb; Cdc42 binding protein kinase beta K08286; COG: COG3264 Small-conductance mechanosensitive channel; Psort location: CytoplasmicMembrane, score:10.00.
  
     0.736
CKO_01124
Hypothetical protein; KEGG: spt:SPA0993 1.7e-33 holE; DNA polymerase III, theta subunit K02345; COG: NOG13893 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96.
  
     0.729
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: medium (42%) [HD]