STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_01714Hypothetical protein; COG: COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component. (423 aa)    
Predicted Functional Partners:
CKO_01715
Hypothetical protein; KEGG: noc:Noc_2489 1.8e-86 sufC; FeS assembly ATPase SufC K09013; COG: COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component.
 
 
 0.999
CKO_01716
Hypothetical protein; COG: COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
 
 
0.998
sufS
Hypothetical protein; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
 
 
 0.994
sufE
Hypothetical protein; Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L- alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process; Belongs to the SufE family.
 
 
 0.985
CKO_04174
Hypothetical protein; KEGG: ssn:SSO_2967 3.1e-192 cysteine sulfinate desulfinase; COG: COG0520 Selenocysteine lyase; Psort location: Cytoplasmic, score:8.96.
 
 
 0.969
CKO_01717
Hypothetical protein; COG: COG0316 Uncharacterized conserved protein; Belongs to the HesB/IscA family.
 
 
 0.909
CKO_00252
Hypothetical protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
  
 0.887
CKO_04175
Hypothetical protein; KEGG: cps:CPS_2211 2.2e-15 putative selenocysteine lyase K02426; COG: COG2166 SufE protein probably involved in Fe-S center assembly.
 
 
 0.714
nfuA
Hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 
 0.670
CKO_00253
Hypothetical protein; COG: COG0316 Uncharacterized conserved protein; Psort location: Cytoplasmic, score:8.96; Belongs to the HesB/IscA family.
  
 
 0.614
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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