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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_01792Hypothetical protein; KEGG: sbo:SBO_1322 1.5e-87 ydjA; hypothetical protein; COG: COG0778 Nitroreductase. (183 aa)    
Predicted Functional Partners:
birA
Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.839
CKO_02166
Hypothetical protein; COG: COG1944 Uncharacterized conserved protein; Psort location: Cytoplasmic, score:8.96.
 
  
 0.787
CKO_04935
Hypothetical protein; KEGG: rru:Rru_A1792 3.8e-84 ABC transporter component K01990; COG: COG1131 ABC-type multidrug transport system, ATPase component; Psort location: CytoplasmicMembrane, score:10.00.
  
  
 0.644
topB
Hypothetical protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...]
 
   
 0.614
selD
Hypothetical protein; Synthesizes selenophosphate from selenide and ATP.
  
    0.604
CKO_01793
Hypothetical protein; KEGG: ecs:ECs2472 2.5e-302 protease IV K04773; COG: COG0616 Periplasmic serine proteases (ClpP class).
       0.560
CKO_03239
Hypothetical protein; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: CytoplasmicMembrane, score:10.00.
  
  
 0.538
CKO_01663
Hypothetical protein; KEGG: ecp:ECP_1597 5.2e-64 lactoylglutathione lyase K01759; COG: COG0346 Lactoylglutathione lyase and related lyases.
  
  
 0.530
CKO_03179
KEGG: stt:t0237 2.9e-61 hypothetical protein K01759; COG: COG0346 Lactoylglutathione lyase and related lyases.
  
  
 0.530
CKO_01599
Hypothetical protein; COG: COG1266 Predicted metal-dependent membrane protease; Psort location: CytoplasmicMembrane, score:10.00.
  
  
 0.510
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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