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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_01944Hypothetical protein; COG: COG3134 Predicted outer membrane lipoprotein. (175 aa)    
Predicted Functional Partners:
CKO_00210
Hypothetical protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrad [...]
  
    0.839
CKO_00327
Hypothetical protein; COG: NOG10065 non supervised orthologous group.
   
  
 0.642
CKO_01945
Hypothetical protein.
       0.544
mtfA
Hypothetical protein; Involved in the regulation of ptsG expression by binding and inactivating Mlc.
  
     0.501
CKO_00776
COG: COG1289 Predicted membrane protein; Psort location: CytoplasmicMembrane, score:10.00.
  
     0.491
CKO_04018
Hypothetical protein; COG: NOG09772 non supervised orthologous group.
  
  
 0.490
CKO_01619
Hypothetical protein; KEGG: spt:SPA1384 1.1e-203 rstB; two component sensor kinase K07639; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score:10.00.
  
     0.432
CKO_00245
Hypothetical protein; KEGG: spz:M5005_Spy_1664 0.0062 PTS system, mannitol (cryptic)-specific IIA component K00890; COG: COG3711 Transcriptional antiterminator; Psort location: Cytoplasmic, score:8.96.
  
     0.429
CKO_01367
Hypothetical protein; COG: NOG17005 non supervised orthologous group.
   
  
 0.422
CKO_04965
COG: COG2982 Uncharacterized protein involved in outer membrane biogenesis.
  
     0.410
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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