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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpoBHypothetical protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). (213 aa)    
Predicted Functional Partners:
CKO_01952
Hypothetical protein; COG: COG5633 Predicted periplasmic lipoprotein.
 
  
 0.971
CKO_01950
Hypothetical protein; KEGG: sec:SC1158 5.2e-80 ycfN; putative cytoplasmic protein K07251; COG: COG0510 Predicted choline kinase involved in LPS biosynthesis; Psort location: Cytoplasmic, score:8.96.
 
  
 0.851
CKO_03220
Hypothetical protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
  
 
 
 0.818
ftsN
Hypothetical protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
   
 0.811
CKO_01953
Hypothetical protein; KEGG: eci:UTI89_C1231 4.1e-55 ycfF; HIT-like protein YcfF K01518; COG: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; Psort location: Cytoplasmic, score:8.96.
  
  
 0.788
mzrA
Hypothetical protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
  
     0.764
CKO_04644
Hypothetical protein; COG: NOG12178 non supervised orthologous group.
  
     0.763
rcsD
Hypothetical protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
  
     0.756
CKO_00260
Hypothetical protein; COG: NOG06208 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96.
  
     0.755
CKO_01942
Hypothetical protein; KEGG: reu:Reut_B4338 0.0030 copper/zinc superoxide dismutase K04565; COG: NOG13874 non supervised orthologous group.
  
     0.755
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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