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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrCHypothetical protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (347 aa)    
Predicted Functional Partners:
pyrD
Hypothetical protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 
 0.992
pyrB
Hypothetical protein; KEGG: sec:SC4315 1.4e-157 pyrB; aspartate carbamoyltransferase, catalytic subunit K00609; COG: COG0540 Aspartate carbamoyltransferase, catalytic chain; Psort location: Cytoplasmic, score:9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
 
 0.987
pyrI
Hypothetical protein; Involved in allosteric regulation of aspartate carbamoyltransferase.
   
 
  0.954
CKO_00943
Hypothetical protein; KEGG: aha:AHA_2602 3.5e-136 dihydroorotase K01465; COG: COG0044 Dihydroorotase and related cyclic amidohydrolases; Psort location: Cytoplasmic, score:8.96.
    
 0.930
CKO_03586
Hypothetical protein; KEGG: btl:BALH_4413 1.3e-74 possible dihydroorotase K01486; COG: COG3964 Predicted amidohydrolase.
     
  0.900
carA
Hypothetical protein; KEGG: eci:UTI89_C0036 1.4e-198 carA; carbamoyl-phosphate synthase small chain K01956; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score:8.96; Belongs to the CarA family.
   
  
 0.717
carB
Hypothetical protein; KEGG: stm:STM0067 0. carB; carbamoyl-phosphate synthase, large subunit K01955; COG: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family.
   
  
 0.706
CKO_01018
Hypothetical protein; KEGG: lic:LIC12268 0.0034 putative glycolate oxidase K00016; COG: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Psort location: Cytoplasmic, score:8.96.
   
  
 0.700
purF
Hypothetical protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.654
upp
Hypothetical protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
   
    0.584
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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