STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_02060Hypothetical protein; KEGG: ngo:NGO2059 2.1e-09 putative peptide methionine sulfoxide reductase K07304:K07305; COG: COG0526 Thiol-disulfide isomerase and thioredoxins. (168 aa)    
Predicted Functional Partners:
CKO_02062
Hypothetical protein; KEGG: xcc:XCC0519 6.7e-56 dsbD; c-type cytochrome biogenesis protein K04084; COG: COG4233 Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis; Psort location: CytoplasmicMembrane, score:10.00.
 
 
 0.963
CKO_02061
Hypothetical protein; KEGG: eba:ebA6610 7.2e-05 dsbC; periplasmic thiol:disulfide interchange protein K03981; COG: COG1651 Protein-disulfide isomerase.
 
 
 0.920
msrA
Hypothetical protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.853
CKO_02554
Hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 0.817
CKO_02758
Hypothetical protein; KEGG: stm:STM0402 2.0e-101 putative thiol - alkyl hydroperoxide reductase K03386; COG: COG0450 Peroxiredoxin; Psort location: Cytoplasmic, score:9.97.
  
 0.817
CKO_03808
Hypothetical protein; Possible subunit of a heme lyase.
  
  
 0.776
CKO_03809
Hypothetical protein; KEGG: stm:STM4281 1.2e-253 nrfE; putative methylase K04016; COG: COG1138 Cytochrome c biogenesis factor; Psort location: CytoplasmicMembrane, score:10.00.
  
  
 0.776
cbpA
Hypothetical protein; DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.
   
 
 0.771
dsbD
Hypothetical protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
  
 
 0.733
CKO_02184
Hypothetical protein; KEGG: ecc:c1025 6.6e-167 trxB; thioredoxin reductase K00384; COG: COG0492 Thioredoxin reductase.
  
 
 0.731
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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